简介：

1980年生于成都。2004年毕业于中国科学技术大学力学与机械工程系，获学士学位；2008年获香港科技大学纳米科学与纳米技术博士学位；之后在美国普林斯顿大学物理系工作，历任博士后研究员，讲师等职务。2012年加入中国科学院物理研究所“百人计划”，任特聘研究员，博士生导师。2015年加入重庆大学物理学院，任教授。

现为国家级青年人才;

国家“973”青年项目首席科学家;

中美癌症物理研究联盟（US-China Physical Oncology Alliance)（筹）执行主任；

曾获中国科学院“卢嘉锡”人才奖，东京工业大学青年科学家奖。

研究方向：

1. 癌症生物物理：基于改变肿瘤微环境的癌症治疗新方法探索；

2. 微流体生物芯片的设计与开发；

3. 自组织机器人集群；

4. 软物质生物物理；

5. 自组织集群行为涌现机理研究。

在研项目：

1. 自然科学基金面上项目（12174041）

“集群机器人活性物质与复杂环境耦合的动力学研究”

2. 自然科学基金面上项目（11974066）

“介观尺度下癌细胞侵袭取向性胶原纤维的动力学研究”

代表性论文：

1. G. Wang , T.V. Phan , S. Li , J. Wang , Y.Peng , G. Chen , J. Qu , D.Goldman , S. A. Levin, K. J. Pienta , S. R. Amend , R. H. Austin, L. Liu, " Robots as Models of Evolving Systems", Proc. Natl. Acad. Sci. USA (PNAS)(2022) 119(12) e2120019119
2. X. Wang, S. Chen, H. Nan, R. Liu, Y. Ding, K. Song, J. Shuai, Q. Fan, Y. Zheng, F. Ye, Y.Jiao, and L. Liu. "Abnormal Aggregation of Invasive Cancer Cells Induced by Collective Polarization and ECM-Mediated Mechanical Coupling in Coculture Systems", Research(2021) 9893131
3. J. Yao, G. Li, Y. Jiao, Y. Zheng, Y. Liu, G. Wang, L. Zhou, H. Zhang, X. Zhang, J. Shuai,Q. Fan, F. Ye, S. Lou, G. Chen, K. Song, Y. Liao and L. Liu, "Biological gel-based microchamber array for tumor cell proliferation and migration studies in well-controlled biochemical gradients", Lab on a Chip (2021) doi ="10.1039/D0LC00951B"
4. Y. Liu, Y. Jiao, Q. Fan, Y. Zheng, G. Li, J. Yao, G. Wang, S. Lou, G. Chen, J. Shuai and L. Liu,"Shannon entropy for time-varying persistence of cell migration", Biophysical Journal (2021) 120, 2552–2565
5. Gao W., Trung V. P., Shengkai L., Michael W., Junle Q., Yan P., Guo C., Daniel I. G., Simon A. L., Robert H. A.,L. Liu, "Emergent Field-Driven Robot Swarm States", Physical Review Letters 126,108002 (2021)
6. Qihui F., Yu Z., Xiaochen W., Ruipei X., Yu D., Boyi W., Xiaoyu Y., Ying L.,L. Liu, Yunliang L., Ming L., Yuanjin Z., Yang J., Fangfu Y, "Dynamically re‐organized collagen fiber bundles transmit mechanical signals and induce strongly correlated cell migration and self‐organization", Angew. Chem. Int. Ed. DOI:https://doi.org/10.1002/anie.202016084 (2021)
7. J. Sun, L. Zhang, L. Cui, X. Luo, G. He, X. Dong, L. He, J. Zhang,J. Sun, G. Chen, Y. Lv, L. Liu, "Gestational age estimation from ultrasound fetal biometrics in China", Clin. Exp. Obstet. Gynecol (47(5): 714-722 (2020)
8. J. Zheng, Y. Cheng, Y. Huang, S. Wang, L. Liu,G. Chen, "Drop impacting on a surface with adjustable wettability based on the dielectrowetting effect", Phys. Fluids32, 097108 (2020)
9. Y. Lv, G. Li, H. Peng, Y. Liu, J. Yao, G. Wang, J. Sun, J. Liu, H. Zhang, G. Chen, L. Liu, "Development of elastic artificial vessels with a digital pulse flow system to investigate the risk of restenosis and vasospasm", Lab on a Chip 20(16):3051-3059(2020)
10. G. Chen, J. Zheng, L. Liu, L. Xu, "Application of Microfluidics in Wearable Devices", Small Methods 1900688 (2019)
11. Y. He, L. Xiong, X. Gao, M. Hai, Y. Liu, G. Wang, G. Chen, J. Shuai, Y. Jiao, X. Zhang, R. Liu, L. Liu, "Morphological quantification of proliferation-to-invasion transition in tumor spheroids", BBA - General Subjects 1864(2019) 129460
12. Y. Zheng, H. Nan, Y. Liu, Q. Fan, X. Wang, R. Liu, L. Liu, "Modeling cell migration regulated by cell extracellular-matrix micromechanical coupling", Physical Review E 100(2019) 043303
13. R. Liu, K. Song, Z. Hu, W. Cao, J. Shuai, S. Chen, H. Nan, Y. Zhen, X. Jiang, H. Zhang, W. Han, Y. Liao, J. Qu, Y. Jiao, Jing Fan, L. Liu, "Diversity of collective migration patterns of invasive breast cancer cells emerging during microtrack invasion", Physical Review E99, 062403 (2019)
14. W. Diao, X. Tong, C. Yang, F. Zhang, C. Bao, C. Hao, L. Liu,M. Li, F. Ye, Q. Fan, J. Wang, Z. Ou-Yang, "Behaviors of glioblastoma cells in in vitro microenvironments", Scientific Reports 9:85(2019)
15. Y. Wu, W. Chen, Z. Wan, A. Djurisic, X. Feng, L. Liu, G. Chen, R. Liu, Z. He, "Multifunctional atomic force probes for Mn2+ doped perovskite solar cells", Journal of Power Sources 425(2019) 130-137 (2019)
16. A. Wu, D. Liao, V. Kirilin, K. Lin, G. Torga, J. Qu, L. Liu, J. Sturm, K. Pienta, R. Austin, "Cancer dormancy and criticality from a game theory perspective", Cancer Convergence DOI 10.1186/s41236-018-0008-0 (2018)
17. H. Xie, Y. Jiao, Q. Fan, M. Hai, J. Yang, Z. Hu, Y. Yang, J. Shuai, G. Chen, R. Liu, L. Liu, "Modeling three-dimensional invasive solid tumor growth in heterogeneous microenvironment under chemotherapy", Plos One 13(10): e0206292 (2018)
18. Y. Wu, W. Chen, Y. Lin, B. Tu, Z. Wu, R. Liu, L. Liu, A. Djuri?i?, Z. He, "General Method To Define the Type of Carrier Transport Materials for Perovskite Solar Cells via Kelvin Probes Microscopy", ACS Appl. Energy Mater. 1, 3984-3991 (2018)
19. Y. Wu, W. Chen, G. Chen, L. Liu, Z. He, R. Liu, "The Impact of Hybrid Compositional Film/Structure on Organic-Inorganic Perovskite Solar Cells”, Nanomaterials 8 (6) doi: 10.3390/nano8060356 (2018)
20. H. Nan, L. Liang, G. Chen, L. Liu, R. Liu, Y. Jiao, "Realizations of highly heterogeneous collagen networks via stochastic reconstruction for micromechanical analysis of tumor cell invasion", Physical Review E 97 (3) 033311 (2018)
21. K. Song, Z. Wang, R. Liu, G. Chen, L. Liu, "Microfabrication-Based Three-Dimensional (3-D) Extracellular Matrix Microenvironments for Cancer and Other Diseases", International Journal of Molecular Science 19 (4) doi:10.3390/ijms19040935 (2018)
22. K. Song, Y. Wu, X. Chen, Y. He, L. Liu, G. Chen, R. Liu, "SKPM study on organic-inorganic perovskite materials", AIP Advances 8 (3) 0351114 (2018)
23. Y. Liu, X. Zhang, Y. Wu, W. Liu, X. Li, R. Liu, L. Liu, J. Shuai, "Derivation of persistent time for anisotropic migration of cells", Chin. Phys. B Vol. 26, No. 12 (2017) 128707 (2017)
24. Q. Fan, R. Liu, Y. Jiao, C. Tian, James D. Farrell, X. Wang, F. Zhang, W. Yuan, H. Han, J. Chen, Y Yang, X. Zhang, F. Ye, M. Li, Z. Ouyang, and L. Liu, "A novel 3-D bio-microfluidic system mimicking in vivo heterogeneous tumour microstructure reveals complex tumourstroma interactions", Lab on a Chip DOI:10.1039/C7LC00191F (2017)
25. W. Han, S. Chen, W.Yuan, Q. Fan, J. Tian, X. Wang, L. Chen, X. Zhang, W. Wei, R. Liu, Junle Qu, Y. Jiao, Robert H.Austin, and L. Liu, "Oriented collagen fibers direct tumor cell intravasation", Proc. Natl. Acad. Sci. USA (2016)
26. R. Liu, Y.Li, and L. Liu, "Single molecule fluorescence spectroscopy for quantitative biological applications", Quantitative Biology 177–191 (2016)
27. G. Wang , X. Wang , T. Liu , R. Liu , and L. Liu, "In vitro experimental models and their molding technology of tumor cell", Acta. Phys. Sin. 65,188700 (2016)
28. H. Wang, J. Liu, X. Zheng, X. Rong, X. Zheng, H. Peng, Z. S. Li, M. Li, L. Liu, "Three-dimensional virtual surgery models for percutaneous coronary intervention (PCI) optimization strategies", Sci. Rep. 5,10945 (2015)
29. J. Zhu, L. Liang, Y. Jiao, L. Liu, "Enhanced Invasion of Metastatic Cancer Cells via Extracellular Matrix Interface", PLoS ONE 10,1371 (2015)
30. L. Liu, G. Duclos, B. Sun, J. Lee, A. Wu, Y. Kam, E. D. Sontag, H. A. Stone, J. C. Sturm, R. A. Gatenby and R. H. Austin, "Minimization of thermodynamic costs in cancer cell invasion", Proc. Natl. Acad. Sci. USA 10.1073 (2013)
31. L. Liu, B. Sun, K. Aw Yong, R. Getzenberg, H. Stone and R. Austin, “Probing the invasiveness of prostate cancer cells in a 3D microfabricated landscape”, Proc. Natl. Acad. Sci. USA 108:6853–6856 (2011)（高亮文章）
32. L. Liu, K. Loutherback, D. Liao, D. Yeater, G. Lambert, A. Estevez-Torres, J. Sturm, R. Getzenberg and R. Austin, “A microfluidic device for continuous cancer cell culture and passage with hydrodynamic forces”, Lab on a Chip 10, 1807-1813 (2010)
33. L. Liu, W. Cao, J. Wu, W. Wen, D. C. Chang and P. Sheng, “Design and Integration of an All-in-One Biomicrofluidic Chip”, Biomicrofluidics 2,034103 (2008)
34. L. Liu, S. Peng, W. Wen and P. Sheng, “Micro Thermo Indicators and Optical-Electronic Temperature Control for Microfluidic Applications”, Appl. Phys. Lett. 91, 093513 (2007)
35. L. Liu, S. Peng, W. Wen and P. Sheng, “ Paperlike thermochromic display”, Appl. Phys. Lett. 90 213508 (2007)
36. L. Liu, S. Peng, X. Niu and W. Wen, “Microheater fabricated from a conducting composite”, Appl. Phys. Lett. 89, 223521 (2006)
37. L. Liu, X. Niu, W. Wen and P. Sheng, “Electrorheological fluid-actuated flexible platform”, Appl. Phys. Lett. 88, 173505 (2006)
38. L. Liu, X. Chen, X. Niu, W. Wen, and P. Sheng, “Electrorheological fluid actuated microfluidic pump”, Appl. Phys. Lett. 89, 083505 (2006)
39. L. Liu, X. Huang, C. Shen, Z. Liu, J. Shi, W. Wen and P. Sheng, “Parallel-field electrorheological clutch: Enhanced high shear rate performance”, Appl. Phys. Lett. 87, 104106 (2005)